How are mice poisoned in pest control?

How are mice poisoned in pest control? - briefly

Professional pest control relies mainly on anticoagulant baits (e.g., bromadiolone, brodifacoum) that mice eat, leading to fatal internal bleeding within several days; acute poisons such as zinc phosphide are also employed, releasing toxic phosphine gas after ingestion.

How are mice poisoned in pest control? - in detail

Rodent control programs employ chemical agents specifically formulated to eliminate mice. The most common categories are anticoagulants, acute neurotoxins, and metabolic disruptors.

  • Anticoagulant compounds – first‑generation (warfarin, chlorophacinone) and second‑generation (bromadiolone, difenacoum). These interfere with vitamin K recycling, causing fatal internal bleeding after several days of sub‑lethal ingestion. Bait pellets or blocks are typically laced with 0.005–0.025 % active ingredient, allowing a mouse to consume a dose sufficient to trigger hemorrhage without immediate aversion.

  • Acute neurotoxins – bromethalin, zinc phosphide, and strychnine. Bromethalin disrupts mitochondrial ATP production, leading to rapid paralysis and death within 24–48 hours. Zinc phosphide releases phosphine gas when it contacts stomach acid; the gas damages cellular respiration, causing death in a few hours. Baits containing these agents are highly palatable and often coated with attractants such as grain or cheese.

  • Metabolic disruptors – sodium fluoroacetate (1080) and phosphonic acid derivatives. These interfere with the citric‑acid cycle, producing lethal energy failure. Formulations are usually granular or liquid, applied to runways or burrow entrances.

Delivery methods aim to maximize consumption while minimizing non‑target exposure:

  1. Stationary bait stations – enclosed units that admit only rodents of a specific size, protecting birds and pets. Stations are placed along walls, behind appliances, and in concealed corners.
  2. Bait blocks and pellets – scattered in concealed areas where mice travel. Low‑profile design reduces detection by non‑target species.
  3. Dusts and granules – applied to nesting material or tunnels. Particles adhere to fur and are ingested during grooming.
  4. Liquid formulations – sprayed on surfaces frequented by rodents; mice ingest residues while grooming or feeding.

Safety protocols require:

  • Placement at least 2 m from child‑accessible zones.
  • Use of tamper‑resistant containers.
  • Monitoring for bait depletion and removal of uneaten product after 48 hours.
  • Compliance with local pesticide regulations, which often restrict second‑generation anticoagulants to professional applicators.

Resistance management involves rotating active ingredients every 4–6 weeks and integrating non‑chemical measures such as sealing entry points, removing food sources, and employing traps. This integrated approach reduces the likelihood of tolerance development and enhances overall efficacy.