How is mouse fever transmitted from mice to humans?

How is mouse fever transmitted from mice to humans? - briefly

Humans acquire mouse‑borne hemorrhagic fever mainly by inhaling aerosolized urine, feces, or saliva from infected rodents, and also through direct skin contact with contaminated materials or rodent bites. Infection can further result from consuming food or water tainted with these secretions.

How is mouse fever transmitted from mice to humans? - in detail

Rodent‑borne fever is primarily caused by hantaviruses carried by wild mice. Human infection occurs when viral particles enter the body through the respiratory or mucosal surfaces. The most common pathways are:

  • Inhalation of aerosolized material – dried urine, feces, or saliva from infected rodents become airborne when disturbed by cleaning, sweeping, or ventilation. Breathing in these particles delivers the virus directly to the lungs.
  • Direct contact with contaminated surfaces – touching rodent droppings, nests, or bedding and then rubbing the eyes, nose, or mouth transfers the pathogen to mucous membranes.
  • Bite or scratch wounds – rare, but a bite from an infected mouse can introduce the virus directly into the bloodstream.
  • Consumption of contaminated food or water – ingestion of food items that have been contaminated with rodent excreta can lead to gastrointestinal exposure, though this route is less frequent.

The virus survives outside the host for several days in cool, dry conditions, increasing the risk in storage areas, barns, and homes with rodent infestations. Activities that disturb settled rodent debris, such as moving boxes, cleaning attics, or renovating basements, markedly raise the chance of aerosol formation.

Preventive measures focus on eliminating rodent habitats and minimizing exposure:

  1. Seal entry points to buildings; use steel‑wool or metal flashing to block gaps.
  2. Maintain low food and water availability for rodents by storing supplies in rodent‑proof containers.
  3. Employ traps or professional pest‑control services to reduce population density.
  4. When cleaning areas with suspected contamination, wear disposable gloves, masks (N95 or higher), and eye protection; wet the area with a disinfectant solution before sweeping to suppress dust.
  5. Dispose of dead rodents and contaminated materials in sealed bags, then incinerate or discard according to local regulations.

Early recognition of symptoms—fever, muscle aches, gastrointestinal upset, followed by respiratory distress—combined with prompt medical evaluation can improve outcomes. Laboratory testing for hantavirus antibodies or PCR confirms diagnosis, guiding supportive care in intensive settings.