How do rats grow day by day?

How do rats grow day by day? - briefly

Rats typically gain 2–3 g of body weight each day during the first four weeks, a result of accelerated cell division and a high basal metabolism. After weaning, daily weight gain declines to roughly 0.5–1 g as growth hormones shift toward maturation.

How do rats grow day by day? - in detail

Rats increase body mass rapidly after birth, gaining roughly 2–3 g per day during the first two weeks. The newborn, weighing about 1.5–2 g, is altricial: eyes remain closed, fur is sparse, and motor coordination is limited. Within 24 hours, the neonate begins to nurse, receiving maternal milk rich in protein, fat, and lactose, which supplies the energy required for cellular proliferation.

During days 1–4, the primary focus is on thermoregulation and digestive system activation. The stomach enlarges, gastric enzymes such as pepsin appear, and the intestinal villi expand to improve nutrient absorption. By day 5, whiskers emerge, and the rat starts to exhibit righting reflexes, indicating maturation of the central nervous system.

From day 6 to day 10, skeletal growth accelerates. Growth plates in long bones produce new cartilage, later ossified under the influence of growth hormone and insulin‑like growth factor‑1 (IGF‑1). Limb length increases by approximately 0.5 mm daily, while the skull expands to accommodate brain development.

Between days 11 and 14, weaning begins. The infant reduces reliance on milk and starts to ingest solid food, introducing dietary fibers that stimulate gut microbiota diversification. This transition supports immune system maturation and further weight gain of 3–4 g per day.

Key developmental milestones:

  • Day 1: First suckling, initiation of milk intake.
  • Day 3: Appearance of vibrissae, onset of thermogenic shivering.
  • Day 5: Development of righting and grasping reflexes.
  • Day 7: Initiation of skeletal ossification at growth plates.
  • Day 10: Emergence of exploratory locomotion.
  • Day 12: Commencement of solid food consumption.
  • Day 14: Completion of weaning, body weight reaches 30–35 g.

Hormonal regulation drives these changes. Prolactin sustains lactation, while cortisol peaks around day 8 to facilitate metabolic adaptation to solid food. Thyroid hormones rise steadily, promoting basal metabolic rate and skeletal maturation.

Environmental variables, such as ambient temperature, litter size, and nutrition quality, modulate growth velocity. Cooler temperatures increase metabolic demand, potentially slowing weight gain, whereas abundant, high‑quality milk accelerates it. Larger litters induce competition for resources, resulting in slightly reduced individual growth rates.

Overall, rat development follows a predictable, tightly regulated schedule, with each day contributing specific physiological advances that collectively transform a fragile neonate into a self‑sufficient juvenile within two weeks.