How do rats behave before death?

How do rats behave before death? - briefly

In the hours preceding mortality, rats exhibit marked lethargy, reduced movement, diminished food and water consumption, and a hunched posture. Additional signs may include altered grooming, irregular respiration, and vocalizations indicating discomfort.

How do rats behave before death? - in detail

Rats display a recognizable pattern of behavioral alterations as they approach the end of life. Activity levels decline markedly; animals spend prolonged periods immobile in corners or under bedding. Grooming frequency diminishes, and when grooming occurs it is often incomplete or erratic, indicating reduced self‑maintenance. Social interaction drops sharply; individuals isolate from conspecifics, avoiding contact even when food or nesting material is shared.

Locomotor changes become evident. Rats exhibit slower gait, frequent pauses, and reduced exploratory trips to the periphery of the cage. When movement does occur, it is often uncoordinated, with stumbling or dragging of hind limbs. Postural adjustments include a hunched back, lowered head, and a tendency to curl into a compact ball, which conserves energy and protects vital organs.

Vocalizations shift toward low‑frequency squeaks and occasional prolonged whines, reflecting discomfort or distress. Respiratory patterns become irregular, with shallow breaths interspersed with brief apneas. In the final hours, stereotyped convulsive episodes may arise, characterized by rapid, repetitive limb movements and facial twitching.

Key observable signs:

  • Decreased overall activity and increased immobility
  • Fragmented or absent grooming behavior
  • Withdrawal from group members and reduced social contact
  • Slowed, unsteady locomotion and frequent pauses
  • Hunched posture, lowered head, and curled body shape
  • Low‑frequency vocalizations and occasional prolonged whines
  • Irregular, shallow respiration with intermittent pauses
  • Terminal convulsive bursts with rapid limb twitching

These indicators provide a reliable framework for recognizing the approach of death in laboratory or pet rats, allowing timely humane intervention and accurate interpretation of experimental outcomes.