At what age do rats reach maturity?

At what age do rats reach maturity? - briefly

Rats typically become sexually mature between five and six weeks of age, with full adult development occurring by eight to twelve weeks. This timeline applies to most laboratory strains under standard housing conditions.

At what age do rats reach maturity? - in detail

Rats attain sexual competence during the adolescent phase, typically between five and six weeks after birth. Hormonal surges trigger the onset of spermatogenesis in males and the first estrous cycles in females. By the seventh week, females exhibit regular estrous cycles lasting four to five days, indicating full reproductive capability.

Physical development continues alongside reproductive maturation. Skeletal growth plates close around eight to ten weeks, marking the transition to adult body size. Dental eruption reaches completion by the same period, supporting the animal’s capacity for sustained gnawing and foraging.

Key developmental milestones:

  • 5–6 weeks: Initiation of sperm production; first ovulation in females.
  • 6–7 weeks: Regular estrous cycles in females; peak testosterone levels in males.
  • 8–10 weeks: Closure of growth plates; full adult morphology achieved.
  • 12 weeks: Stabilization of body weight; behavioral patterns typical of mature rodents established.

Variations occur among strains. Laboratory strains such as Sprague‑Dawley often mature slightly earlier, reaching reproductive readiness around 45 days, whereas wild‑derived populations may require up to 60 days due to environmental stressors and nutrition differences.

Environmental factors influence the timeline. Adequate protein intake, optimal temperature (20–24 °C), and low‑stress housing accelerate maturation, while caloric restriction or chronic stress can delay hormonal activation and postpone the onset of fertility.

In summary, rats become reproductively functional between five and six weeks of age, with full physical adulthood established by ten weeks, subject to genetic and environmental modulation.