How are diseases transmitted from mice?

How are diseases transmitted from mice? - briefly

Mice spread pathogens via direct contact, contaminated droppings, urine, saliva, and by carrying ectoparasites such as fleas and ticks that bite humans. These transmission routes can result in infections including hantavirus, leptospirosis, salmonellosis, and plague.

How are diseases transmitted from mice? - in detail

Rodents serve as reservoirs for a wide array of pathogens that can reach humans and domestic animals through several well‑documented pathways. Direct physical contact, such as bites or scratches, introduces infectious agents present in saliva or blood into the recipient’s tissue. Contaminated excreta—urine, feces, and nesting material—pose a primary risk when aerosolized particles are inhaled, a route responsible for hantavirus pulmonary syndrome and certain strains of leptospirosis. Ingestion of food or water tainted by droppings leads to gastrointestinal infections, exemplified by Salmonella enterica and Lymphocytic Choriomeningitis Virus.

Ectoparasites that feed on mice, including fleas, mites, and ticks, act as biological or mechanical vectors, transmitting Yersinia pestis, the causative agent of plague, and various rickettsial organisms. Indirect transmission occurs via fomites: objects or surfaces that become contaminated with rodent secretions and later handled without proper hygiene. Vertical transmission, though less common, can occur when pregnant females pass pathogens such as hantavirus to offspring through the placenta, perpetuating the infection cycle within rodent populations.

Key disease agents and their principal transmission routes are summarized below:

  • Hantavirus – inhalation of aerosolized urine or feces
  • Leptospira spp. – contact with contaminated water or soil, skin abrasions
  • Salmonella spp. – ingestion of food contaminated by droppings
  • Lymphocytic Choriomeningitis Virus – bite, scratch, or contact with contaminated secretions
  • Yersinia pestis – flea bites, handling of infected rodents

Effective control measures focus on eliminating rodent access to food storage areas, sealing entry points, maintaining stringent sanitation, and employing integrated pest‑management strategies to reduce vector populations. Personal protective equipment, such as gloves and masks, is essential when handling rodents or cleaning contaminated environments to prevent occupational exposure.