How to treat subcutaneous mange in rats? - briefly
Administer a topical acaricide such as selamectin or ivermectin at the veterinary‑recommended dose and enforce strict hygiene by cleaning bedding and isolating affected rats. Provide supportive care, monitor for secondary infections, and ensure adequate nutrition to aid recovery.
How to treat subcutaneous mange in rats? - in detail
Subcutaneous sarcoptic mange in rats results from infestation by Sarcoptes scabiei var. ratti. The parasite burrows within the dermis, producing alopecia, erythema, pruritus, and secondary bacterial infection. Accurate diagnosis relies on clinical signs, skin scrapings examined microscopically, and, when necessary, histopathology.
Therapeutic protocol begins with systemic acaricides. Recommended agents and dosages:
- Ivermectin: 0.2 mg/kg body weight, administered subcutaneously or orally, repeat after 7 days; a third dose may be given if lesions persist.
- Selamectin: 0.2 mg/kg, applied topically once; repeat after 14 days for complete eradication.
- Moxidectin: 0.2 mg/kg, oral formulation, single dose; monitor for residual lesions and retreat if needed.
Topical treatments support systemic therapy:
- Lime sulfur dip: 1 % solution, applied to affected areas for 10 minutes, repeat weekly for three applications.
- Benzoyl peroxide 5 % cream: applied twice daily to localized lesions to reduce bacterial colonization.
Supportive measures enhance recovery:
- Environmental decontamination: clean cages, replace bedding, and disinfect surfaces with a 1 % bleach solution; repeat cleaning every 48 hours during treatment.
- Nutritional support: provide a balanced diet enriched with vitamin E and omega‑3 fatty acids to promote skin healing.
- Antimicrobial therapy: administer enrofloxacin 10 mg/kg subcutaneously once daily for 5 days if secondary infection is confirmed.
Monitoring includes weekly assessment of lesion size, hair regrowth, and behavior. Successful resolution typically occurs within 3–4 weeks of consistent therapy. Persistent itching after parasite clearance may indicate allergic dermatitis; antihistamines such as diphenhydramine 1 mg/kg orally every 12 hours can be employed for symptomatic relief.