How should worms be treated in rats? - briefly
Use a veterinary‑approved anthelmintic (e.g., fenbendazole, ivermectin, or pyrantel pamoate) at the species‑specific dosage and repeat treatment as indicated by follow‑up fecal examinations. Ensure proper dosing, monitor for adverse reactions, and maintain hygiene to prevent reinfection.
How should worms be treated in rats? - in detail
Worm infestations in laboratory or pet rats require accurate diagnosis, appropriate anthelmintic selection, correct dosing, and ongoing monitoring.
Diagnosis is based on fecal flotation or sedimentation to identify ova, PCR for species confirmation, and clinical signs such as weight loss, dull coat, or gastrointestinal disturbance. Post‑mortem examination may be necessary for definitive identification of adult parasites.
Therapeutic agents commonly employed include:
- Pyrantel pamoate – effective against nematodes such as Syphacia muris and Aspiculuris spp.; oral dose 5 mg/kg once daily for three consecutive days.
- Fenbendazole – broad‑spectrum benzimidazole; 50 mg/kg orally for five days, or 100 mg/kg for a single dose in severe cases.
- Ivermectin – active against certain cestodes and nematodes; 0.2 mg/kg subcutaneously, repeat after 7 days if needed.
- Levamisole – alternative for resistant nematodes; 2 mg/kg orally, administered twice daily for three days.
Drug choice depends on parasite species, infection intensity, and the rat’s health status. Dosages must be calculated per kilogram of body weight and administered with a palatable vehicle to ensure ingestion. Monitoring fecal samples 7–10 days after treatment confirms eradication; a second course may be required for persistent infections.
Supportive care includes:
- Providing a high‑quality diet rich in protein and fiber to promote gut health.
- Maintaining a clean environment: regular cage cleaning, removal of fecal contamination, and disinfection with a 1 % bleach solution.
- Implementing quarantine for new arrivals and testing before introduction to established colonies.
Preventive strategies involve routine fecal screening every 4–6 weeks in breeding colonies, prophylactic administration of fenbendazole at 25 mg/kg in feed during high‑risk periods, and strict biosecurity to limit exposure to intermediate hosts.
Record-keeping of treatment regimens, outcomes, and any adverse reactions is essential for longitudinal health management and compliance with institutional animal care guidelines.